Is there a way on the combobox to set a minimum number of characters that are entered before it calls for the XML?
I’m using autocomplete mode where it is calling a file with the options for the combobox.
Combo API doesn’t provide this functionality. You can modify the dhtmlxcombo.js as follows:
locate the filterSelf method and replace the highlighted line:  
dhtmlXCombo.prototype.filterSelf = function(mode)
   {
      var text=this.getComboText();
      if (this._xml){
with this one:
      if (this._xml && (text.length >= MINIMUM_NUMBER)){
Where MINIMUM_NUMBER is the necessary number of characters.