How to update and save cell value using function in dhtmlx spreadsheet

my data is serialized like this format
image
. but I’m unable to update the value .
so how I can update value using the only column names.

Could you please, clarify do you need to update the value in your spreadsheet or in the serialized data.

update the value in the spreadsheet.

Please, try to use
spreadsheet._grid.data.getItem(row_number)[column_number]=“newValue”
Here is the example:
https://snippet.dhtmlx.com/daklwexm