Open local database from web

Hi, mine it’s a general question. I read many document about using local database (on a pen drive) but I can’t understand how to open a local file (like Sqlite) from a USB pen drive and parse the date into a Grid.
There are other methods to read/update local data?? Not on web server.

Unfortunately the dhtmlxgrid(treegrid) is a web application and it should be lanched from a web’server.
you may use only the solutions available for web applications.